OpenAI Launches GPT-5.5 Bio Bug Bounty to Stress-Test Biosecurity Guardrails

OpenAI has opened a structured bug bounty program specifically targeting GPT-5.5's biosecurity safeguards, inviting qualified researchers to probe the model's resistance to biological threat-related queries. This is a notable step toward adversarial red-teaming becoming a formalized, public-facing practice rather than an internal-only process, and it sets a template other labs may follow. For developers building applications in life sciences, healthcare, or dual-use domains, this signals that OpenAI is applying heightened scrutiny to bio-related outputs — which will affect what the model will and won't do in those contexts. The bounty also implies that biosecurity is now treated as a first-class safety category on par with CSAM or weapons uplift, shaping future policy and API usage terms. Developers should monitor findings from this program, as discovered jailbreaks typically lead to capability restrictions that can affect adjacent legitimate use cases.